Mutations in gyrA & parC genes of Shigella flexneri 2a determining the fluoroquinolone resistance
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چکیده
منابع مشابه
Mutations in gyrA & parC genes of Shigella flexneri 2a determining the fluoroquinolone resistance
Shigellosis or bacillary dysentery is caused by a group of facultative anaerobic Gram-negative rods of the genus Shigella. Worldwide, about 165 million cases of shigellosis were reported annually (99% occurring in the developing world) with one million associated deaths 1. Approximately 60 per cent of deaths involve children younger than five years 2. Four Shigella species, S. dysenteriae, S. f...
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Objective(s): We investigated the contribution of gyrA and parC mutational mechanism in decreased ciprofloxacin susceptibility of Acinetobacter baumannii isolated from burn wound infections. Materials and Methods: Ciprofloxacin susceptibility of 50 A. baumannii isolates was evaluated by disk diffusion and agar dilution methods. PCR and sequencing were performed for detection of mutation in gyr...
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Mutations in the quinolone resistance-determining regions (QRDR) in chromosomal gyrA and parC genes and fluoroquinolone susceptibility profiles were investigated in quinolone-resistant Enterobacteriaceae isolated from community and hospitalized patients in the Brazilian Southeast region. A total of 112 nalidixic acid-resistant enterobacterial isolates collected from 2000 to 2005 were investigat...
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ژورنال
عنوان ژورنال: Indian Journal of Medical Research
سال: 2015
ISSN: 0971-5916
DOI: 10.4103/0971-5916.160722